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长春胺-克芦米通对脑血管功能不全患者双盲研究的临床、心理及神经生理学结果(作者译)

[Clinical, psychological and neurophysiological results of double-blind study on vincamine-cromesilate in patients with cerebro-vascular insufficiency (author's transl)].

作者信息

Mikus P

出版信息

Arzneimittelforschung. 1978;28(11):2165-8.

PMID:582924
Abstract

In a long-term double-blind cross-over design 26 patients with amnestic syndrome due to cerebro-vascular insufficiency were submitted to vincamine-cromesilate (Vincaryl) and placebo treatment. The efficiency of vincamine was proved by mildly ameliorated psychometric patterns, biochemically by decreased cholesterol level and ophthalmodynamographically by slight increase of pulsation capacity. By means of EMG, ECG and EEG clinic side effects were excluded.

摘要

在一项长期双盲交叉设计中,26例因脑血管供血不足导致遗忘综合征的患者接受了长春胺葡糖醛酸酯(长春西汀)和安慰剂治疗。长春胺的疗效通过心理测量模式略有改善得到证实,生化方面通过胆固醇水平降低得到证实,眼动态造影方面通过搏动能力略有增加得到证实。通过肌电图、心电图和脑电图排除了临床副作用。

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