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某些非甾体抗炎药对大鼠和豚鼠因卵清蛋白引起的皮肤过敏反应的作用。

Action of some non-steroid anti-inflammatory drugs on skin anaphylaxis due to ovalbumin in the rat and the guinea pig.

作者信息

Tarayre J P, Lauressergues H

出版信息

Arzneimittelforschung. 1979;29(5):774-6.

PMID:582976
Abstract

Six non-steroidal anti-inflammatory drugs, metiazinic and niflumic acids, iburofen, indometacin, ketoprofen and phenylbutazone, were tested on two anaphylactic skin reactions to ovalbumin: the passive reaction in the rat and active anaphylaxis in the guinea pig. In the rat, only niflumic and metiazinic acids reduced very slightly the reaction. In the guinea pig, ibuprofen, phenylbutazone, metiazinic acid and ketoprofen had good activity. The results are discussed.

摘要

对六种非甾体抗炎药,即甲氮嗪酸、氟灭酸、布洛芬、吲哚美辛、酮洛芬和保泰松,进行了两种对卵清蛋白过敏的皮肤反应测试:大鼠被动反应和豚鼠主动过敏反应。在大鼠中,只有氟灭酸和甲氮嗪酸使反应略有降低。在豚鼠中,布洛芬、保泰松、甲氮嗪酸和酮洛芬具有良好的活性。对结果进行了讨论。

相似文献

1
Action of some non-steroid anti-inflammatory drugs on skin anaphylaxis due to ovalbumin in the rat and the guinea pig.某些非甾体抗炎药对大鼠和豚鼠因卵清蛋白引起的皮肤过敏反应的作用。
Arzneimittelforschung. 1979;29(5):774-6.
2
Comparison of the effects of a non-steroidal anti-inflammatory agent, an immunosuppressive, a corticosteroid and an immunomodulator on various immunological and non-immunological inflammatory experimental models.一种非甾体抗炎药、一种免疫抑制剂、一种皮质类固醇和一种免疫调节剂对各种免疫和非免疫炎症实验模型影响的比较。
Arch Int Pharmacodyn Ther. 1979 Nov;242(1):159-76.
3
Protective effect of furosemide combined with non-steroidal anti-inflammatory drugs administered by inhalation route on guinea-pigs anaphylaxis model.
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[Basic studies on the anti-allergic and anti-inflammatory action of xylofuranoside derivatives. 1].[木糖呋喃糖苷衍生物抗过敏和抗炎作用的基础研究。1]
Arerugi. 1969 Feb;18(2):112-6.
5
[Effects of quinoline and pyrazolone anti-inflammatory derivatives on passive anaphylaxis in guinea pigs].
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Suppression by antihistamine of passive cutaneous anaphylaxis produced with anaphylactic antibody in the guinea pig.
J Immunol. 1967 Feb;98(2):230-5.
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Acute effects of deflazacort and its metabolite 21-desacetyl-deflazacort on allergic reactions.地夫可特及其代谢产物21-去乙酰地夫可特对过敏反应的急性影响。
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[The anti-anaphylactic action of potassium channel openers and its mechanism].[钾通道开放剂的抗过敏作用及其机制]
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Comparison of the action of antiphlogistics, anti-anaphylactics and antihistaminics in the carrageenin- & immunologically-induced inflammation model in the rat and in passive cutaneous anaphylaxis.在大鼠角叉菜胶诱导及免疫诱导炎症模型和被动皮肤过敏反应中抗炎药、抗过敏药及抗组胺药作用的比较
Agents Actions Suppl. 1982;10:273-87.

引用本文的文献

1
Strain-dependency of leukotriene C4 generation from isolated lungs of immunized mice.免疫小鼠离体肺组织白三烯C4生成的应变依赖性
Br J Pharmacol. 1994 Aug;112(4):1230-6. doi: 10.1111/j.1476-5381.1994.tb13215.x.
2
Lotifazole (F 1686), a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum.洛替法唑(F 1686),一种具有独特药理谱的非甾体抗炎药。
Agents Actions. 1984 Jan;14(1):93-101. doi: 10.1007/BF01966840.
3
Action of mannitol in various immunological experimental models.甘露醇在各种免疫学实验模型中的作用。
Agents Actions. 1979 Oct;9(4):369-74. doi: 10.1007/BF01970663.