[Absence of a teratogenic effect of sodium nitroprusside in wistar rats and rabbits (author's transl)].

In a series of experiments sodium nitroprusside (NNP) was tested in the prenatal phases of development in two animal species with regard to possible teratogenic and embryo-toxic effects. A total of 571 offsprings of rats and 48 offsprings of rabbits was investigated. The application of NNP in the prenatal experiment produced no evidence of an embryo-toxic or teratogenic effect, respectively, in rats and rabbits.