外消旋沙利度胺的色谱分离及其对映体的致畸活性（作者译）
[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)].
作者信息
Blaschke G, Kraft H P, Fickentscher K, Köhler F
出版信息
Arzneimittelforschung. 1979;29(10):1640-2.
PMID:583234
Abstract
Racemic thalidomide is chromatographically separated on optically active polyamide giving both enantiomers. After i.p. administration only the S-(-)-enantiomer is teratogenic on SWS mice and Natal rats.
摘要
消旋沙利度胺在光学活性聚酰胺上进行色谱分离，得到两种对映体。腹腔注射后，只有S-(-)-对映体对SWS小鼠和纳塔尔大鼠具有致畸性。
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