• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

必需脂肪酸缺乏对发育中大鼠脑内[1(-14)C]亚麻酸代谢转化的影响。

The effect of essential fatty acid deprivation on the metabolic transformations of [1(-14)C]linolenate in developing rat brain.

作者信息

Dwyer B E, Bernsohn J

出版信息

Biochim Biophys Acta. 1979 Dec 18;575(3):309-17. doi: 10.1016/0005-2760(79)90099-7.

DOI:10.1016/0005-2760(79)90099-7
PMID:583255
Abstract

Linolenic acid undergoes rapid metabolism in the brain of 21-day-old rats. Radioactivity is rapidly transferred from linolenic acid to the C20 (n--3) fatty acids while that in docosapentaenoic acid (22 : 5 n--3) and docosahexaenoic acid (22 : 6 n--3) gradually increases. A greater proportion of the radioactivity is associated with the polyunsaturated and less with saturated and monounsaturated fatty acids in essential fatty acid-deprived rats relative to controls.

摘要

在21日龄大鼠的大脑中,亚麻酸经历快速代谢。放射性物质迅速从亚麻酸转移至C20(n-3)脂肪酸,而二十二碳五烯酸(22:5 n-3)和二十二碳六烯酸(22:6 n-3)中的放射性物质则逐渐增加。与对照组相比,在必需脂肪酸缺乏的大鼠中,更大比例的放射性物质与多不饱和脂肪酸相关,而与饱和脂肪酸和单不饱和脂肪酸相关的比例较小。

相似文献

1
The effect of essential fatty acid deprivation on the metabolic transformations of [1(-14)C]linolenate in developing rat brain.必需脂肪酸缺乏对发育中大鼠脑内[1(-14)C]亚麻酸代谢转化的影响。
Biochim Biophys Acta. 1979 Dec 18;575(3):309-17. doi: 10.1016/0005-2760(79)90099-7.
2
The incorporation of [1-14C]linolenate into lipids of developing rat brain during essential fatty acid deprivation.在必需脂肪酸缺乏期间,[1-14C]亚麻酸掺入发育中大鼠脑脂质的情况。
J Neurochem. 1979 Mar;32(3):833-8. doi: 10.1111/j.1471-4159.1979.tb04567.x.
3
Effects of dietary linolenate on the fatty acid composition of brain lipids in rats.膳食亚麻酸对大鼠脑脂质脂肪酸组成的影响。
Lipids. 1986 Nov;21(11):697-701. doi: 10.1007/BF02537243.
4
Biosynthesis of polyunsaturated fatty acids in the developing brain: I. Metabolic transformations of intracranially administered 1-14C linolenic acid.
Lipids. 1976 Jan;11(1):67-71. doi: 10.1007/BF02532586.
5
Metabolism of gamma-linolenic acid in essential fatty acid-deficient rats.γ-亚麻酸在必需脂肪酸缺乏大鼠体内的代谢
J Nutr. 1977 Apr;107(4):519-24. doi: 10.1093/jn/107.4.519.
6
Essential fatty acids and fetal brain growth.必需脂肪酸与胎儿大脑发育
Lancet. 1976 Feb 28;1(7957):452-3. doi: 10.1016/s0140-6736(76)91476-8.
7
Growth and cerebral lipid composition during maturation of rats fed varying levels of linoleate and linolenate.在喂养不同水平亚油酸和亚麻酸的大鼠成熟过程中的生长及脑脂质组成
Nutr Rev. 1975 Sep;33(9):278-81. doi: 10.1111/j.1753-4887.1975.tb05114.x.
8
[Effect of the linolenic acid content of the mother's diet on the polyunsaturated fatty acid composition of subcellular fractions in brain development in the rat].[母体饮食中亚麻酸含量对大鼠脑发育中亚细胞组分多不饱和脂肪酸组成的影响]
Ann Nutr Metab. 1983;27(3):233-41. doi: 10.1159/000176665.
9
Inhibition of gap junction-mediated intercellular communication by alpha-linolenate.α-亚麻酸对间隙连接介导的细胞间通讯的抑制作用。
Am J Physiol. 1991 Jul;261(1 Pt 1):C161-8. doi: 10.1152/ajpcell.1991.261.1.C161.
10
High fat diets varying in ratios of polyunsaturated to saturated fatty acid and linoleic to linolenic acid: a comparison of rat neural and red cell membrane phospholipids.多不饱和脂肪酸与饱和脂肪酸以及亚油酸与亚麻酸比例不同的高脂饮食:大鼠神经细胞膜和红细胞膜磷脂的比较
J Nutr. 1986 May;116(5):718-25. doi: 10.1093/jn/116.5.718.

引用本文的文献

1
Essential fatty acid uptake and metabolism in the developing rodent brain.发育中啮齿动物大脑中的必需脂肪酸摄取与代谢
Lipids. 1996 Mar;31 Suppl:S103-7. doi: 10.1007/BF02637060.
2
Dietary supplementation of undernourished rats with soy or safflower oil: effects on myelin polyunsaturated fatty acids.用大豆油或红花油对营养不良的大鼠进行膳食补充:对髓磷脂多不饱和脂肪酸的影响。
Metab Brain Dis. 1986 Jun;1(2):157-64. doi: 10.1007/BF00999385.