Longley J R
Calif Med. 1965 Nov;103(5):343-4.
Determination of the prostatic acid phosphatase is, theoretically, a specific test for carcinoma of the prostate, but the present laboratory techniques have produced too many false positives and false negatives to be dependable. There may be inhibitors or enzymes that interfere with these tests. Until more exact enzymes are discovered, the present acid phosphatases should not be depended upon as a criterion for the type of surgical operation in carcinoma of the prostate, nor, without biopsy, should they be taken as an indication of prostatic malignant disease.
理论上,前列腺酸性磷酸酶的测定是前列腺癌的一项特异性检测,但目前的实验室技术产生了过多的假阳性和假阴性结果,因而不可靠。可能存在干扰这些检测的抑制剂或酶。在发现更精确的酶之前,目前的酸性磷酸酶不应被用作前列腺癌手术类型的判断标准,并且在没有活检的情况下,也不应将其作为前列腺恶性疾病的指标。