Bell T K, Bridges J M, Nelson M G
J Clin Pathol. 1965 Sep;18(5):611-3. doi: 10.1136/jcp.18.5.611.
The absorption of vitamin B(12) following the simultaneous administration of (58)Co B(12) and a complex of (57)Co B(12) with human gastric juice was assessed by measurement of urinary excretion of radioactivity. Sixteen control subjects, 13 patients with pernicious anaemia, and four who had had total gastrectomy were studied. The method proved a reliable means of detecting those with intrinsic factor deficiency.
通过测量放射性物质的尿排泄量,评估了同时给予(58)钴维生素B12和(57)钴维生素B12与人胃液的复合物后维生素B12的吸收情况。对16名对照受试者、13名恶性贫血患者和4名接受全胃切除术的患者进行了研究。该方法被证明是检测内因子缺乏者的可靠手段。