既往照射对血液淋巴细胞转化的影响。
Effect of previous irradiation on the transformation of blood lymphocytes.
作者信息
Millard R E
出版信息
J Clin Pathol. 1965 Nov;18(6):783-5. doi: 10.1136/jcp.18.6.783.
Abstract
The transformation of blood lymphocytes in cultures with phytohaemagglutinin was studied in five patients before and at intervals up to 18 to 19 months after therapeutic irradiation of the abdomen and pelvis (dose of x rays 3,200r to 4,475r). In one patient, all cultures showed satisfactory lymphocyte transformation. In four patients transformation was depressed following irradiation. In three of these patients the duration of the depression was short; in one patient it was prolonged for over a year. The poor response of the lymphocytes to phytohaemagglutinin was not associated either with leucopenia or with a high incidence of cells with chromosome abnormalities in the cultures.
摘要
对5例患者在腹部和盆腔进行治疗性照射（X线剂量为3200伦琴至4475伦琴）之前以及照射后间隔长达18至19个月期间，研究了用植物血凝素进行培养时血液淋巴细胞的转化情况。在1例患者中，所有培养物均显示淋巴细胞转化情况良好。在4例患者中，照射后转化受到抑制。其中3例患者抑制持续时间较短；1例患者抑制持续时间超过1年。淋巴细胞对植物血凝素反应不佳与白细胞减少以及培养物中染色体异常细胞的高发生率均无关。
相似文献
1
Effect of previous irradiation on the transformation of blood lymphocytes.既往照射对血液淋巴细胞转化的影响。
J Clin Pathol. 1965 Nov;18(6):783-5. doi: 10.1136/jcp.18.6.783.
2
[Effects of ultraviolet irradiation on the lymphocytes in the blood. Inhibition of uridine incorporation].[紫外线照射对血液中淋巴细胞的影响。尿苷掺入的抑制作用]
C R Acad Hebd Seances Acad Sci D. 1967 Jul 10;265(2):173-6.
3
X-irradiation of equine peripheral blood lymphocytes stimulated with phytohaemagglutinin in vitro.体外对用植物血凝素刺激的马外周血淋巴细胞进行X射线照射。
Int J Radiat Biol Relat Stud Phys Chem Med. 1976 Sep;30(3):229-46. doi: 10.1080/09553007614551011.
4
The effect of in vitro irradiation on the responses of human lymphocytes to PHA, PPD and allogeneic cells.体外照射对人淋巴细胞对PHA、PPD和同种异体细胞反应的影响。
Strahlentherapie. 1975 May;149(5):504-12.
5
[Effect of prolonged administration of irradiated food on rabbits. Peripheral blood studies].[长期给予辐照食品对家兔的影响。外周血研究]
Arch Vet Ital. 1971 Feb 28;22(1):1-9.
6
Letter: The lymphocyte response to phytohaemagglutinin after in vitro irradiation.信件：体外照射后淋巴细胞对植物血凝素的反应。
Br J Radiol. 1974 May;47(557):297. doi: 10.1259/0007-1285-47-557-297-b.
7
8
"Antigenic" disparity between lymphocytes and autologous phytohaemagglutinin-induced lymphoblasts.
Lancet. 1971 Oct 30;2(7731):977. doi: 10.1016/s0140-6736(71)90296-0.
9
[The effect of roentgen rays on the proliferative activity of the stem cells developed in culture of lymphocytes of normal human blood].[伦琴射线对正常人血液淋巴细胞培养中发育的干细胞增殖活性的影响]
Boll Soc Ital Biol Sper. 1964 Dec 31;40(24):Suppl:2183-6.
10
Modification of renal homograft rejection by irradiation.辐射对同种肾移植排斥反应的影响
Transplantation. 1967 Jul;5(4):Suppl:1174-91. doi: 10.1097/00007890-196707001-00055.
引用本文的文献
1
Serial changes in lymphocyte subsets in patients with newly diagnosed high grade astrocytomas treated with standard radiation and temozolomide.新诊断的高级别星形细胞瘤患者在标准放疗和替莫唑胺治疗下淋巴细胞亚群的连续变化。
J Neurooncol. 2017 Nov;135(2):343-351. doi: 10.1007/s11060-017-2580-z. Epub 2017 Jul 29.
2
[Investigations of unspecific immune reactivity in patients with head and neck carcinoma (author's transl)].头颈部癌患者非特异性免疫反应的研究（作者译）
Arch Otorhinolaryngol. 1981;232(2):145-63. doi: 10.1007/BF00505034.
3
Lymphocyte transformation and chromosome studies in Hodgkin's disease.霍奇金病的淋巴细胞转化及染色体研究
Br Med J. 1967 Sep 16;3(5567):704-8. doi: 10.1136/bmj.3.5567.704.
4
Interferon, antibody, and other host factors in herpes zoster.带状疱疹中的干扰素、抗体及其他宿主因素。
J Clin Invest. 1972 May;51(5):1170-8. doi: 10.1172/JCI106910.
5
Lymphocyte transformation in diseases of lymphoid tissue.淋巴组织疾病中的淋巴细胞转化
Proc R Soc Med. 1970 Apr;63(4):355-7. doi: 10.1177/003591577006300411.
6
[PHA-stimulation of blood lymphocytes in patients with multiple sclerosis during combined therapy with aldosterone and spirolactone derivatives].[多发性硬化症患者在醛固酮和螺内酯衍生物联合治疗期间血液淋巴细胞的PHA刺激]
Klin Wochenschr. 1973 Mar 15;51(6):286-7. doi: 10.1007/BF01467819.
7
[Lymphocyte culture and its relation to clinical problems].[淋巴细胞培养及其与临床问题的关系]
Klin Wochenschr. 1969 Aug 1;47(15):789-99. doi: 10.1007/BF01882304.
8
A comparison of the acute effects of radiation therapy, including or excluding the thymus, on the lymphocyte subpopulations of cancer patients.放射治疗（包括或不包括胸腺）对癌症患者淋巴细胞亚群的急性影响比较。
J Clin Invest. 1975 Jul;56(1):88-97. doi: 10.1172/JCI108084.
9
Blood lymphocyte subpopulations in breast cancer patients following radiotherapy.放疗后乳腺癌患者的血液淋巴细胞亚群
Clin Exp Immunol. 1977 Jul;29(1):36-42.
10
T- and B-lymphocyte subpopulations following radiotherapy for invasive squamous cell carcinoma of the uterine cervix.子宫颈浸润性鳞状细胞癌放疗后的T淋巴细胞和B淋巴细胞亚群
Clin Exp Immunol. 1978 Jul;33(1):159-65.
本文引用的文献
1
Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes.植物血凝素：正常人白细胞培养中细胞有丝分裂的启动剂。
Cancer Res. 1960 May;20:462-6.
2
THE ROUTE OF RE-CIRCULATION OF LYMPHOCYTES IN THE RAT.大鼠淋巴细胞的再循环途径
Proc R Soc Lond B Biol Sci. 1964 Jan 14;159:257-82. doi: 10.1098/rspb.1964.0001.
3
Myelosclerosis: an autoimmune disease.
Lancet. 1963 Apr 6;1(7284):773. doi: 10.1016/s0140-6736(63)91599-x.
4
Tuberculin-induced mitosis in peripheral blood leucocytes.结核菌素诱导外周血白细胞有丝分裂。
Lancet. 1963 Mar 23;1(7282):637-8. doi: 10.1016/s0140-6736(63)91275-3.
5
Preliminary reports of chromosome studies during radiation therapy.放射治疗期间染色体研究的初步报告。
Am J Roentgenol Radium Ther Nucl Med. 1962 Mar;87:555-8.
6
The human small lymphocyte: its possible pluripotential quality.人类小淋巴细胞：其可能的多能性特质。
Lancet. 1962 Apr 21;1(7234):829-32. doi: 10.1016/s0140-6736(62)91841-x.
7
Types and rates of x-ray-induced chromosome aberrations in human blood irradiated in vitro.体外照射的人体血液中X射线诱导的染色体畸变类型和发生率
Proc Natl Acad Sci U S A. 1962 Apr 15;48(4):522-32. doi: 10.1073/pnas.48.4.522.
8
X-ray-induced chromosome damage in man.X射线诱发的人类染色体损伤。
Lancet. 1960 Oct 15;2(7155):849-51. doi: 10.1016/s0140-6736(60)91911-5.
9
Chromosome preparations of leukocytes cultured from human peripheral blood.从人外周血培养的白细胞的染色体标本制备。
Exp Cell Res. 1960 Sep;20:613-6. doi: 10.1016/0014-4827(60)90138-5.
Zotero 插件