Gault M H, Steiner G
Can Med Assoc J. 1965 Nov 20;93(21):1101-5.
Recently it has been observed that the activity of certain enzymes in serum and urine may be increased after renal infarction. Although aortography or selective renal angiography should be the diagnostic corner-stone on which one would proceed to embolectomy, it is possible that enzyme assays may serve as laboratory aids to suggest or confirm the diagnosis. This paper reviews the few existing clinical and experimental studies and reports on two patients who had a total of three episodes of renal infarction. Serial determinations after one episode showed increased activity of serum oxaloacetic glutamic transaminase (SGOT) and of lactic acid dehydrogenase (LDH) and alkaline phosphatase in the serum and urine; some elevated serum LDH and SGOT values were recorded after the other two infarctions. The time of onset and duration of these increases are discussed, and the possible difficulty in differentiating renal from myocardial infarction is illustrated.
最近观察到，肾梗死发生后，血清和尿液中某些酶的活性可能会升高。尽管主动脉造影或选择性肾血管造影应是进行栓子切除术的诊断基石，但酶测定有可能作为实验室辅助手段来提示或确诊。本文回顾了现有的少量临床和实验研究，并报告了两名患者共发生三次肾梗死的情况。一次梗死发作后的系列测定显示，血清草酰乙酸谷氨酸转氨酶（SGOT）、乳酸脱氢酶（LDH）以及血清和尿液中的碱性磷酸酶活性增加；另外两次梗死发作后记录到一些血清LDH和SGOT值升高。文中讨论了这些升高的起始时间和持续时间，并举例说明了区分肾梗死和心肌梗死可能存在的困难。
