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The "induction" of leukocyte and erythrocyte dihydrofolate reductase by methotrexate. II. Clinical and pharmacologic studies.

作者信息

Bertino J R, Cashmore A, Fink M, Calabresi P, Lefkowitz E

出版信息

Clin Pharmacol Ther. 1965 Nov-Dec;6(6):763-70. doi: 10.1002/cpt196566763.

DOI:10.1002/cpt196566763
PMID:5846409
Abstract
摘要

相似文献

1
The "induction" of leukocyte and erythrocyte dihydrofolate reductase by methotrexate. II. Clinical and pharmacologic studies.甲氨蝶呤对白细胞和红细胞二氢叶酸还原酶的“诱导”作用。II. 临床与药理学研究。
Clin Pharmacol Ther. 1965 Nov-Dec;6(6):763-70. doi: 10.1002/cpt196566763.
2
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.二氢叶酸还原酶的“诱导”：“诱导”的人红细胞、白细胞酶及正常骨髓酶的纯化与性质
Cancer Res. 1970 Sep;30(9):2372-8.
3
Dihydrofolic reductase in human blood cells. II. Enzyme activity after amethopterin and actinomycin C administration.人血细胞中的二氢叶酸还原酶。II. 给予氨甲蝶呤和放线菌素C后的酶活性
Enzymol Biol Clin (Basel). 1967;8(5):363-78. doi: 10.1159/000458223.
4
Regulation of dihydrofolate reductase and other folate-requiring enzymes.二氢叶酸还原酶及其他需要叶酸的酶的调节
Adv Enzyme Regul. 1968;6:335-49. doi: 10.1016/0065-2571(68)90021-6.
5
Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.暴露于甲氨蝶呤后培养的哺乳动物细胞中二氢叶酸还原酶活性的增加。
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1632-7. doi: 10.1073/pnas.58.4.1632.
6
Triamterene-induced elevation of dihydrofolate reductase activity in human leukocytes.氨苯蝶啶引起人白细胞中二氢叶酸还原酶活性升高。
Biochem Pharmacol. 1968 Mar;17(3):481-4. doi: 10.1016/0006-2952(68)90260-8.
7
Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.暴露于叶酸拮抗剂后培养的哺乳动物细胞中二氢叶酸还原酶、胸苷酸合成酶和胸苷激酶的升高。
Cancer Res. 1976 Jul;36(7 PT 1):2442-9.
8
Trimethoprim-induced elevation of dihydrofolate reductase activity in human leukocytes.甲氧苄啶诱导人白细胞中二氢叶酸还原酶活性升高。
Enzyme. 1978;23(3):154-63. doi: 10.1159/000458570.
9
Effect of 11-oxahomofolate and its reduced derivatives on human dihydrofolate reductase and on human cells having different amounts of dihydrofolate reductase.
Biochem Pharmacol. 1982 Jan 15;31(2):255-6. doi: 10.1016/0006-2952(82)90220-9.
10
The effect of folate antagonists on dihydrofolate reductase activity demonstrated cytochemically.用细胞化学方法证实叶酸拮抗剂对二氢叶酸还原酶活性的影响。
Br J Haematol. 1974 Oct;28(2):209-16. doi: 10.1111/j.1365-2141.1974.tb06655.x.

引用本文的文献

1
Synthesis and Different Effects of Biotinylated PAMAM G3 Dendrimer Substituted with Nimesulide in Human Normal Fibroblasts and Squamous Carcinoma Cells.尼美舒利取代的生物素化 PAMAM G3 树枝状大分子的合成及其在人正常成纤维细胞和鳞状癌细胞中的不同作用。
Biomolecules. 2019 Sep 1;9(9):437. doi: 10.3390/biom9090437.
2
Entero-hepatic cycling of methotrexate estimated by use of the D-isomer as a reference marker.以D-异构体作为参考标记物估算甲氨蝶呤的肠肝循环。
Eur J Clin Pharmacol. 1984;26(1):103-7. doi: 10.1007/BF00546716.
3
Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
甲氨蝶呤多聚谷氨酸在人乳腺癌细胞中的细胞内药代动力学。4-氨基-10-甲基蝶酰谷氨酸4和4-氨基-10-甲基蝶酰谷氨酸5对二氢叶酸还原酶的选择性保留及较少的解离性结合。
J Clin Invest. 1983 Sep;72(3):773-8. doi: 10.1172/JCI111048.
4
[Effect and istribution of methotrexate in the human organism during leukemia treatment].[白血病治疗期间甲氨蝶呤在人体中的作用及分布]
Klin Wochenschr. 1968 Mar 15;46(6):281-96. doi: 10.1007/BF01738686.
5
Rat folic acid reductase activity during the perinatal period, in newborns, and after trimethoprim administration.围产期、新生儿期及给予甲氧苄啶后大鼠叶酸还原酶活性
Naunyn Schmiedebergs Arch Pharmacol. 1972;274(3):229-37. doi: 10.1007/BF00501932.
6
Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.暴露于甲氨蝶呤后培养的哺乳动物细胞中二氢叶酸还原酶活性的增加。
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1632-7. doi: 10.1073/pnas.58.4.1632.
7
Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.人小细胞肺癌细胞系对甲氨蝶呤敏感性的决定因素。
J Clin Invest. 1985 Oct;76(4):1323-9. doi: 10.1172/JCI112106.