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Rat folic acid reductase activity during the perinatal period, in newborns, and after trimethoprim administration.

作者信息

Schulz R

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1972;274(3):229-37. doi: 10.1007/BF00501932.

DOI:10.1007/BF00501932
PMID:4262779
Abstract
摘要

相似文献

1
Rat folic acid reductase activity during the perinatal period, in newborns, and after trimethoprim administration.围产期、新生儿期及给予甲氧苄啶后大鼠叶酸还原酶活性
Naunyn Schmiedebergs Arch Pharmacol. 1972;274(3):229-37. doi: 10.1007/BF00501932.
2
Inhibition of rat folic acid reductase activity activity by trimethoprim during the later stages of gestation.甲氧苄啶在妊娠后期对大鼠叶酸还原酶活性的抑制作用。
Naunyn Schmiedebergs Arch Pharmacol. 1973;278(2):227-30. doi: 10.1007/BF00500653.
3
[Activity of the trimethoprim-sulfamethoxazole association in experimental toxoplasmosis in mice. Histochemical study].
Boll Ist Sieroter Milan. 1973 Jan-Feb;52(1):70-6.
4
Observations on the thyroid gland in rats following the administration of sulfamethoxazole and trimethoprim.磺胺甲恶唑和甲氧苄啶给药后大鼠甲状腺的观察
Toxicol Appl Pharmacol. 1973 Mar;24(3):351-63. doi: 10.1016/0041-008x(73)90041-0.
5
[Comparative studies on the effect of antibacterial substances on inflammation and wound healing in rats].[抗菌物质对大鼠炎症和伤口愈合影响的比较研究]
Wien Klin Wochenschr. 1972 May 5;84(18):288-91.
6
Inhibition of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductases by 2,4-diamino-5-[2-methoxy-5-(omega-carboxyalkyloxy)benzyl]pyrimidines: marked improvement in potency relative to trimethoprim and species selectivity relative to piritrexim.2,4-二氨基-5-[2-甲氧基-5-(ω-羧基烷氧基)苄基]嘧啶对卡氏肺孢子虫、刚地弓形虫和鸟分枝杆菌二氢叶酸还原酶的抑制作用：相对于甲氧苄啶，其效力显著提高，相对于乙胺嘧啶，具有种属选择性。
J Med Chem. 2002 Jan 3;45(1):233-41. doi: 10.1021/jm010407u.
7
Cloning and characterization of a novel trimethoprim-resistant dihydrofolate reductase from a nosocomial isolate of Staphylococcus aureus CM.S2 (IMCJ1454).从金黄色葡萄球菌医院分离株CM.S2（IMCJ1454）中克隆并鉴定一种新型耐甲氧苄啶二氢叶酸还原酶
Antimicrob Agents Chemother. 2005 Sep;49(9):3948-51. doi: 10.1128/AAC.49.9.3948-3951.2005.
8
2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine analogues of trimethoprim as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.甲氧苄啶的2,4-二氨基-6,7-二氢-5H-环戊并[d]嘧啶类似物作为卡氏肺孢子虫和刚地弓形虫二氢叶酸还原酶的抑制剂
J Med Chem. 1998 Mar 12;41(6):913-8. doi: 10.1021/jm970614n.
9
[Activity of the trimethoprim-sulfamethoxazole association in experimental toxoplasmosis in mice. Histological and immuno-histological study].
Boll Ist Sieroter Milan. 1973 Jan-Feb;52(1):60-9.
10
[Effect of the drug combination trimethoprim-sulfamethoxazole on the intestinal flora of man in short- and long-term administration].[复方磺胺甲恶唑短期和长期给药对人体肠道菌群的影响]
Arzneimittelforschung. 1973 May;23(5):704-8.

引用本文的文献

1
Inhibition of rat folic acid reductase activity activity by trimethoprim during the later stages of gestation.甲氧苄啶在妊娠后期对大鼠叶酸还原酶活性的抑制作用。
Naunyn Schmiedebergs Arch Pharmacol. 1973;278(2):227-30. doi: 10.1007/BF00500653.
2
Dihydrofolate reductase and thymidylate synthetase activities in the liver of rabbit foetuses during the haemapoietic period.造血期兔胎儿肝脏中二氢叶酸还原酶和胸苷酸合成酶的活性。
Biochem J. 1976 Jun 1;155(3):713-5. doi: 10.1042/bj1550713.

本文引用的文献

1
THE "INDUCTION" OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN.用氨甲蝶呤治疗的患者白细胞和红细胞中二氢叶酸还原酶活性的“诱导”
J Clin Invest. 1963 Apr;42(4):466-75. doi: 10.1172/JCI104735.
2
VARIATION IN THE ACTIVITY OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYMES IN RATS IN RELATION TO THE AGE.大鼠肝脏微粒体药物代谢酶活性随年龄的变化
Biochem Pharmacol. 1964 Jul;13:1037-51. doi: 10.1016/0006-2952(64)90100-5.
3
LEVELS OF DIHYDROFOLATE REDUCTASE AND THE FORMATE-ACTIVATING ENZYME ACTIVITIES IN GUINEA PIG TISSUES BEFORE AND AFTER AMETHOPTERIN ADMINISTRATION.
氨甲蝶呤给药前后豚鼠组织中二氢叶酸还原酶水平及甲酸盐激活酶活性
Biochem Pharmacol. 1964 Feb;13:225-33. doi: 10.1016/0006-2952(64)90140-6.
4
EARLY ESTROGEN EFFECTS ON NEWLY SYNTHESIZED RNA AND PHOSPHOLIPID IN SUBCELLULAR FRACTIONS OF RAT UTERI.早期雌激素对大鼠子宫亚细胞组分中新合成RNA和磷脂的影响。
Arch Biochem Biophys. 1963 Dec;103:418-23. doi: 10.1016/0003-9861(63)90431-4.
5
CYTOLOGIC CHANGES IN FETAL AND NEONATAL HEPATIC CELLS OF THE MOUSE.小鼠胎儿和新生儿肝细胞的细胞学变化
Ann N Y Acad Sci. 1963 Dec 30;111:87-103. doi: 10.1111/j.1749-6632.1963.tb36950.x.
6
The anabolic steroids.合成代谢类固醇。
Clin Pharmacol Ther. 1960 Jul-Aug;1:464-82.
7
Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.二氢叶酸还原酶活性增加作为白血病耐药的可能基础。
Nature. 1961 Jan 7;189:39-42. doi: 10.1038/189039a0.
8
Enzymatic reduction of folic acid and dihydrofolic acid to tetrahydrofolic acid.酶促将叶酸和二氢叶酸还原为四氢叶酸。
J Biol Chem. 1957 Oct;228(2):1031-8.
9
Some dietary and hormonal effects on maternal, foetal and placental weights in the rat.一些饮食和激素对大鼠母体、胎儿及胎盘重量的影响。
J Endocrinol. 1953 Jan;9(1):68-75. doi: 10.1677/joe.0.0090068.
10
The role of hormonal and dietary factors in the formation of excess ribonucleic acid in the livers of pregnant rats.
J Endocrinol. 1953 Jan;9(1):52-67. doi: 10.1677/joe.0.0090052.