[Cystostatic drug sensitivity testing of primary cultures of human tumours (author's transl)].

One to eight week-old primary tissue cultures of human tumours (1 rhabomysarcoma, 1 renal adenocarcinoma, 1 hymphogranuloma, 2 melanomas) and cultures of chicken embryo cells and HeLa-cells were tested for their sensitivity to chemotherapeutic agents. The drugs tested were: vincristine, actinomycin D, adriblastine, bleomycin. The drug effect was recorded by registration of morphological changes and, in some cultures by a change in the 3-H-thymidine incorporation. The cultures showed a variable reaction to vincristine, a good response to actinomycin D and adriblastine and were uniformly resistant to bleomycin. Two cultures were pulse labelled with 3-H-thymidine to obtain some data in regard to their growth characteristics.