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手术治疗支气管癌的化疗问题(作者译)

[Chemotherapeutic problems in surgically treated bronchial carcinomas (author's transl)].

作者信息

Wilde J

出版信息

Z Erkr Atmungsorgane. 1975 Feb;142(2):101-9.

PMID:58491
Abstract

There is a report about experiences of a combined surgical and chemotherapeutical therapy with 765 resected patients who had suffered from a bronchial neoplasms. 80 patients had been radically resected and treated with chemotherapy. From 235 palliatively resected persons 124 received cyclophosphamid- or trenimon-therapy after the operation. The 5 years-survival rate of the radically resected persons arose from 50,9 to 58,9% by chemotherapy. In view of the palliatively resected patients the results of 5 years-survival got worse by adjuvant chemotherapy alone or in combination with radiation. But the 3 years-survival results show better relations than the patients without adjuvant therapy. Bronchial stump fistula and empyema as well as other postoperative complications didn't arise by chemotherapy.

摘要

有一份关于765例接受手术和化疗联合治疗的支气管肿瘤切除患者的经验报告。80例患者接受了根治性切除并进行了化疗。在235例接受姑息性切除的患者中,124例在术后接受了环磷酰胺或三胺硫磷治疗。通过化疗,根治性切除患者的5年生存率从50.9%提高到了58.9%。对于姑息性切除的患者,单纯辅助化疗或联合放疗的5年生存结果更差。但3年生存结果显示,与未接受辅助治疗的患者相比,情况更好。化疗未出现支气管残端瘘、脓胸及其他术后并发症。

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[Chemotherapy of bronchial carcinomas (author's transl)].
Z Erkr Atmungsorgane. 1975 Feb;142(2):149-63.

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