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胃对十二指肠电活动的控制——胃十二指肠连接部的功能

Gastric control of duodenal electric activity--the function of the gastroduodenal junction.

作者信息

Abbadessa Urso S, Fileccia R, Montalbano M E

出版信息

Arch Int Physiol Biochim. 1975 Dec;83(5):827-35. doi: 10.3109/13813457509069513.

DOI:10.3109/13813457509069513
PMID:58601
Abstract

An investigation was made into the links between electric activity of antral and of duodeno-jejunal musculature in different functional conditions. The function of the gastroduodenal junction in this linking mechanism was analysed. The following observations were made: (a) in the absence of gastric stimulation, the slow electric activities of stomach and duodenum appear to be completely independent; (b) the gastroduodenal junction evidences no electric activity of its own but is affected by that of the two adjacent structures; (c) chemical stimulation of the gastric mucosa causes activation of the electric and mechanical activity of the stomach and analogous activation of duodenal musculature; this effect is mediated by the gastroduodenal junction; (d) very probably, the transmission of gastric activation to the duodenum is myogenic for it ceases after surgical transection but not after cooling or after ligature. The possible functional role of the pyloric junction in the complex gastroduodenal mechanism is discussed.

摘要

对不同功能状态下胃窦和十二指肠-空肠肌肉组织的电活动之间的联系进行了研究。分析了胃十二指肠连接部在这种连接机制中的作用。得出以下观察结果:(a) 在没有胃刺激的情况下,胃和十二指肠的慢电活动似乎完全独立;(b) 胃十二指肠连接部本身没有电活动,但受相邻两个结构的电活动影响;(c) 胃黏膜的化学刺激会导致胃的电活动和机械活动激活,以及十二指肠肌肉组织的类似激活;这种效应由胃十二指肠连接部介导;(d) 很可能,胃的激活向十二指肠的传递是肌源性的,因为在手术横断后这种传递停止,但在冷却或结扎后不会停止。讨论了幽门连接部在复杂的胃十二指肠机制中可能的功能作用。

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