果蝇中的X连锁6-磷酸葡萄糖酸脱氢酶：亚基关联
X-linked 6-phosphogluconate dehydrogenase in drosophila: subunit associations.
作者信息
Kazazian H H, Young W J, Childs B
出版信息
Science. 1965 Dec 17;150(3703):1601-2. doi: 10.1126/science.150.3703.1601.
PMID:5866658
Abstract
6-Phosphogluconate dehydrogenase (PGD) subunits have been dissociated and reassociated in vitro. The intermediate PGD of the heterozygous phenotype is reproduced by reassociation in vitro of subunits derived from the two types of PGD from homozygous flies. This result has a bearingon gene action in the diploid organism and on the mechanism of dosage compensation in Drosophila melanogaster.
摘要
6-磷酸葡萄糖酸脱氢酶（PGD）亚基已在体外进行了解离和重新结合。杂合子表型的中间型PGD是通过体外将来自纯合果蝇的两种类型PGD的亚基重新结合而产生的。这一结果与二倍体生物中的基因作用以及黑腹果蝇的剂量补偿机制有关。
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