Schwartz B, Kern J
Arch Ophthalmol. 1977 Dec;95(12):2159-65. doi: 10.1001/archopht.1977.04450120065005.
A scanning microdensitometric technique has been developed for measuring the optical density of black and white photographs of the optic disc. From the frequency distribution curve of all the densities of the whole area of the optic disc, a separate peak was identified as corresponding to the area of pallor of the optic disc. Areas of pallor were measured as percentage of areas of the total disc for normal, ocular hypertensive, open-angle glaucoma patients, and those with suspect discs. Median values of percent area of pallor showed correspondence with the clinical diagnosis, the glaucoma patients having significantly larger areas than the normal subjects. The microdensitometric technique provides an objective means of measuring the amount of optic dis pallor. It has potential usefulness for screening and for following up suspect and confirmed glaucomas to determine progression of the disease.
已开发出一种扫描显微密度测定技术，用于测量视盘黑白照片的光密度。从视盘整个区域所有密度的频率分布曲线中，可识别出一个单独的峰值，其对应于视盘苍白区域。对于正常、高眼压、开角型青光眼患者以及疑似视盘异常者，苍白区域以视盘总面积的百分比来测量。苍白区域百分比的中位数与临床诊断相符，青光眼患者的苍白区域明显大于正常受试者。显微密度测定技术提供了一种测量视盘苍白程度的客观方法。它在筛查以及对疑似和确诊青光眼患者进行随访以确定疾病进展方面具有潜在用途。
