Reimold E W, Weinberg A G, Fink C W, Battles N D
Am J Dis Child. 1976 May;130(5):534-41. doi: 10.1001/archpedi.1976.02120060080015.
Polyarteritis was diagnosed in three girls, 9 to 10 years old, by kidney and skin biopsies. They were treated with a combination of prednisone (1.5 to 2 mg/kg) and cyclophosphamide (2 mg/kg) for up to 12 months. The illness was severe in all three, complicated by hypertension, seizures, pulmonary infiltrates, renal failure, or hallucinations. All three patients are alive and well with no or minimal residual symptoms two to three years after therapy was discontinued. The treatment with corticosteroids or with a combination of steroids and immunosuppressive drugs seems to improve the prognosis of polyarteritis considerably.
通过肾脏和皮肤活检，三名9至10岁的女孩被诊断患有结节性多动脉炎。她们接受了泼尼松（1.5至2毫克/千克）和环磷酰胺（2毫克/千克）联合治疗，疗程长达12个月。三名患者病情均严重，伴有高血压、癫痫发作、肺部浸润、肾衰竭或幻觉等并发症。在停止治疗两到三年后，所有三名患者均存活且状况良好，没有或仅有轻微的残留症状。使用皮质类固醇或皮质类固醇与免疫抑制药物联合治疗似乎能显著改善结节性多动脉炎的预后。
