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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Williams R B, Davies N T, McDonald I

Br J Nutr. 1977 Nov;38(3):407-16. doi: 10.1079/bjn19770105.

The accretion of copper and zinc in maternal tissues, conception products and postnatal offspring of the rat was determined at different stages of pregnancy and lactation. 2. Equations relating the weight of the bodies of the developing young and of the amounts of Cu and Zn in them to the time that has elapsed since conception showed that, early in pregnancy, the specific rates of accretion of Cu or Zn were greater than that of weight, but declined more rapidly as development continued. The instantaneous rates of accretion of both metals rose throughout pregnancy but only that of Cu continued to increase during lactation. 3. The amount of Cu in the maternal body rose significantly during pregnancy and declined thereafter, but relatively small changes in its Zn content occurred. 4. The results are discussed in relation to the relative demands for these metals during pregnancy and lactation.

在大鼠妊娠和哺乳的不同阶段，测定了母体组织、受孕产物和产后子代中铜和锌的蓄积情况。2. 将发育中幼体的体重以及其中铜和锌的含量与受孕后经过的时间相关联的方程表明，在妊娠早期，铜或锌的特定蓄积率高于体重的蓄积率，但随着发育的持续，其下降速度更快。两种金属的瞬时蓄积率在整个妊娠期都有所上升，但只有铜的蓄积率在哺乳期继续增加。3. 母体体内铜的含量在妊娠期显著上升，之后下降，但其锌含量变化相对较小。4. 结合妊娠和哺乳期对这些金属的相对需求对结果进行了讨论。

Williams R B, Davies N T, McDonald I

Br J Nutr. 1977 Nov;38(3):407-16. doi: 10.1079/bjn19770105.

The accretion of copper and zinc in maternal tissues, conception products and postnatal offspring of the rat was determined at different stages of pregnancy and lactation. 2. Equations relating the weight of the bodies of the developing young and of the amounts of Cu and Zn in them to the time that has elapsed since conception showed that, early in pregnancy, the specific rates of accretion of Cu or Zn were greater than that of weight, but declined more rapidly as development continued. The instantaneous rates of accretion of both metals rose throughout pregnancy but only that of Cu continued to increase during lactation. 3. The amount of Cu in the maternal body rose significantly during pregnancy and declined thereafter, but relatively small changes in its Zn content occurred. 4. The results are discussed in relation to the relative demands for these metals during pregnancy and lactation.

在大鼠妊娠和哺乳的不同阶段，测定了母体组织、受孕产物和产后子代中铜和锌的蓄积情况。2. 将发育中幼体的体重以及其中铜和锌的含量与受孕后经过的时间相关联的方程表明，在妊娠早期，铜或锌的特定蓄积率高于体重的蓄积率，但随着发育的持续，其下降速度更快。两种金属的瞬时蓄积率在整个妊娠期都有所上升，但只有铜的蓄积率在哺乳期继续增加。3. 母体体内铜的含量在妊娠期显著上升，之后下降，但其锌含量变化相对较小。4. 结合妊娠和哺乳期对这些金属的相对需求对结果进行了讨论。