Salimov R M
Biull Eksp Biol Med. 1977 Nov;84(11):579-82.
Frightening sound stimulation induced alarm and alertness which resulted in weakening of attention to novel environment and increasing of orienting response to the source of the frightening sound. Defense motivation occurring under these conditions failed to alter with the increase of sound loudness. Tranquilizers (diazepam, chlordiazepoxide, benatyzine), antidepressants (amytriptiline, imipramine) and some neuroleptics (trifluoperazine, haloperidol) in a low doze prevented these disturbances. High doses of pentobarbital, chlorpromazine, as well as trifluoperazine and haloperidol did not prevent the mentioned consequences of emotional excitation.
令人恐惧的声音刺激会引发警觉和警醒,这导致对新环境的注意力减弱,而对令人恐惧声音来源的定向反应增强。在这些情况下产生的防御动机并不会随着声音响度的增加而改变。低剂量的镇静剂(地西泮、氯氮卓、贝那替秦)、抗抑郁药(阿米替林、丙咪嗪)和一些抗精神病药(三氟拉嗪、氟哌啶醇)可预防这些干扰。高剂量的戊巴比妥、氯丙嗪,以及三氟拉嗪和氟哌啶醇并不能预防情绪激动所带来的上述后果。