Suppr超能文献

[药物物质对大鼠群体实验中回避反射的影响]

[Effect of pharmacologic substances on the avoidance reflex in a group experiment on rats].

作者信息

Burov Iu V, Kampov-Polevoĭ A B, Salimov R M

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 May-Jun;27(3):530-3.

PMID:899255
Abstract

It has been established that the avoidance reflex is disturbed in rats when performed in the presence of a group of non-learned rats. The degree of the disturbance depends on the number of non-learned animals present and the extent if their emotional excitation. Tranquilizers: diazepam, chlordiazepoxide and benactyzine; neuroleptics: chlorpromazine, trifluoperazine and galoperidol; antidepressants: amitriptilin and imipramine in certain doses, while improving the avoidance reflex in the presence of a group of excited rats, do not affect the disturbance of avoidance in the presence of a group of calm rats. It has been assumed that these drugs prevent the appearance of emotional excitation in learned animals in response to that in the non-learned animals surrounding them.

摘要

已经确定,当在一群未受过训练的大鼠面前进行回避反射时,大鼠的回避反射会受到干扰。干扰程度取决于在场未受过训练动物的数量及其情绪兴奋程度。镇静剂:地西泮、氯氮卓和苯那嗪;抗精神病药:氯丙嗪、三氟拉嗪和氟哌利多;抗抑郁药:某些剂量的阿米替林和丙咪嗪,虽然在一群兴奋的大鼠面前能改善回避反射,但在一群安静的大鼠面前并不影响回避反射的干扰。据推测,这些药物可防止受过训练的动物因周围未受过训练动物的情绪兴奋而出现情绪兴奋。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验