Ado A D, Lukmanova T A, Alekseeva T A, Avdeeva T A
Biull Eksp Biol Med. 1977 Nov;84(11):590-3.
Experimental pollinosis was modelled on guinea pigs. The animals were placed in a cell in which an allergen-water-dialyzed extract of ambrosia pollen was dispersed by means of coaxial pulveriser. Homocytotropic antibodies serving as indices of animal sensitization to the specific allergen formed in guinea pigs as a result of aerosol sensitization. Sensitization of the animals to the ambrosia allergen was accompanied by an increase of sensitivity of the broncho-pulmonary apparatus and was characterized by the bronchospastic reaction in resolving inhalation or inrtavenous injection of a specific allergen.
实验性花粉症以豚鼠为模型。将动物置于一个细胞中，通过同轴喷雾器分散豚草花粉的变应原 - 水透析提取物。作为动物对特定变应原致敏指标的亲同种细胞抗体，是豚鼠通过气溶胶致敏后形成的。动物对豚草变应原的致敏伴随着支气管 - 肺器官敏感性的增加，其特征是在吸入或静脉注射特定变应原消退时出现支气管痉挛反应。
