McCarthy E F, Bonfiglio M, Lawton W
Cancer. 1977 Dec;40(6):3092-6. doi: 10.1002/1097-0142(197712)40:6<3092::aid-cncr2820400650>3.0.co;2-n.
A case of a malignant phenochromocytoma of the organ of Zuckerkandl is reported. There was a solitary functional metastasis in the left femur, which was treated by hip disarticulation after removal of the primary. The patient is asymptomatic and free of further metastases after 3 years. Other reported cases of solitary metastases from malignant pheochromocytomas are cited. These occurred most frequently in the skeleton system, which is the most common site of distant metastases in malignant pheochromocytoma. The reported case and the review of the literature indicate that solitary or limited metastatic lesions should be treated surgically by partial or, when possible, complete resection.
本文报告了一例发生于主动脉旁嗜铬体的恶性嗜铬细胞瘤。左侧股骨出现孤立性功能性转移灶，原发肿瘤切除后行髋关节离断术对其进行治疗。患者无症状，3年后未出现进一步转移。文中引用了其他报道的恶性嗜铬细胞瘤孤立性转移病例。这些转移最常发生在骨骼系统，而骨骼系统是恶性嗜铬细胞瘤远处转移最常见的部位。本报道病例及文献回顾表明，对于孤立性或局限性转移病灶，应通过部分切除或尽可能完整切除进行手术治疗。
