• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

博来霉素在人脑肿瘤中的摄取情况。

Uptake of bleomycin by human brain tumours.

作者信息

Hayakawa T, Ushio Y, Morimoto K, Hasegawa H, Mogami H

出版信息

J Neurol Neurosurg Psychiatry. 1976 Apr;39(4):341-9. doi: 10.1136/jnnp.39.4.341.

DOI:10.1136/jnnp.39.4.341
PMID:58971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC492283/
Abstract

The uptake of bleomycin (BLM) by various types of brain tumours after intravenous or intrathecal administration was investigated by bioassay in 67 patients. The correlation between the BLM distribution and the type and characteristics of brain tumours was studied.

摘要

通过生物测定法对67例患者静脉内或鞘内给药后各种类型脑肿瘤对博来霉素(BLM)的摄取情况进行了研究。研究了BLM分布与脑肿瘤类型及特征之间的相关性。

相似文献

1
Uptake of bleomycin by human brain tumours.博来霉素在人脑肿瘤中的摄取情况。
J Neurol Neurosurg Psychiatry. 1976 Apr;39(4):341-9. doi: 10.1136/jnnp.39.4.341.
2
The uptake, distribution and anti-tumor activity of bleomycin in gliomas in the mouse.
Eur J Cancer (1965). 1974 Mar;10(3):137-42. doi: 10.1016/0014-2964(74)90145-5.
3
[Uptake of bleomycin by human brain tumors].[博来霉素在人脑肿瘤中的摄取情况]
Nihon Gan Chiryo Gakkai Shi. 1974 Nov 20;9(4):419-26.
4
[Uptake of bleomycin by ethylnitrosourea-induced rat brain tumors (author's transl)].[博来霉素被乙基亚硝基脲诱导的大鼠脑肿瘤摄取(作者译)]
No To Shinkei. 1979 Aug;31(8):779-85.
5
A clinical trial of intravenous bleomycin in the treatment of brain tumors.静脉注射博来霉素治疗脑肿瘤的临床试验。
Int J Clin Pharmacol Biopharm. 1975 Dec;12(4):419-26.
6
[Concentration of bleomycin in the brain tumor tissue determined by bioassay].[通过生物测定法测定脑肿瘤组织中博来霉素的浓度]
Rinsho Shinkeigaku. 1972 Apr;12(4):185-90.
7
[A new treatment of malignant brain tumor -1: local injection of bleomycin (author's transl)].恶性脑肿瘤的一种新疗法 -1:博来霉素局部注射(作者译)
No Shinkei Geka. 1981 Dec;9(13):1487-93.
8
Bleomycin hydrolase activity and cytotoxicity in human tumors.人肿瘤中的博来霉素水解酶活性与细胞毒性。
Cancer Res. 1982 Oct;42(10):4026-31.
9
[57Co-bleomycin kinetics after local and systemic administration].[局部及全身给药后57钴-博来霉素的动力学]
Dtsch Zahnarztl Z. 1980 Jan;35(1):96-8.
10
Intracellular distribution of (14C)bleomycin and the cytokinetic effects of bleomycin in the mouse tumor.(14C)博来霉素在小鼠肿瘤中的细胞内分布及博来霉素的细胞动力学效应。
Cancer Res. 1976 Jul;36(7 PT 1):2248-53.

引用本文的文献

1
Pharmacokinetics following intraventricular administration of chemotherapy in patients with neoplastic meningitis.肿瘤性脑膜炎患者脑室内给予化疗后的药代动力学。
Clin Pharmacokinet. 2005;44(1):1-31. doi: 10.2165/00003088-200544010-00001.
2
A critique of the role of the blood-brain barrier in the chemotherapy of human brain tumors.血脑屏障在人类脑肿瘤化疗中作用的批判性分析
J Neurooncol. 1994;20(2):121-39. doi: 10.1007/BF01052723.
3
Clinical pharmacokinetics of cerebrospinal fluid.脑脊液的临床药代动力学
Clin Pharmacokinet. 1982 Jul-Aug;7(4):312-35. doi: 10.2165/00003088-198207040-00003.
4
Bleomycin and brain tumors. A review.博来霉素与脑肿瘤。综述。
J Neurooncol. 1983;1(3):249-55. doi: 10.1007/BF00165609.
5
Studies on the intracerebral injection of bleomycin free and entrapped within liposomes in the rat.关于在大鼠脑内注射游离博来霉素及包裹于脂质体中的博来霉素的研究。
J Neurol Neurosurg Psychiatry. 1984 Jun;47(6):585-9. doi: 10.1136/jnnp.47.6.585.
6
Clinical relevance of pharmacokinetics.药代动力学的临床相关性。
Clin Pharmacokinet. 1980 Mar-Apr;5(2):105-36. doi: 10.2165/00003088-198005020-00001.
7
A potential application for the intracerebral injection of drugs entrapped within liposomes in the treatment of human cerebral gliomas.脂质体包裹药物脑内注射在人类脑胶质瘤治疗中的潜在应用。
J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1213-9. doi: 10.1136/jnnp.48.12.1213.
8
Interstitial chemotherapy for brain tumors: review.脑肿瘤的间质化疗:综述
J Neurooncol. 1991 Feb;10(1):57-74. doi: 10.1007/BF00151247.

本文引用的文献

1
The effect of anticancer agents on nervous tissue.
Cancer Chemother Rep. 1962 Feb;16:543-4.
2
Localization of methyl-bis(2-chloroethyl-1,2-C14)amine hydrochloride in nervous tissue after intravenous injection or regional cerebral perfusion in dogs.犬静脉注射或脑局部灌注盐酸甲基 - 双(2 - 氯乙基 - 1,2 - C14)胺后在神经组织中的定位
Cancer Chemother Rep. 1961 Apr;11:29-32.
3
Biological studies on bleomycin A.博来霉素A的生物学研究。
J Antibiot (Tokyo). 1967 Jul;20(3):149-55.
4
Metabolism of radioactive cyclophosphamide. Animal tests and clinical studies.放射性环磷酰胺的代谢。动物试验与临床研究。
Cancer. 1967 May;20(5):896-9. doi: 10.1002/1097-0142(1967)20:5<896::aid-cncr2820200551>3.0.co;2-d.
5
Biological studies on individual bleomycins.对单个博来霉素的生物学研究。
J Antibiot (Tokyo). 1968 Oct;21(10):592-602. doi: 10.7164/antibiotics.21.592.
6
Studies on bleomycin.博来霉素的研究
Cancer. 1967 May;20(5):891-5. doi: 10.1002/1097-0142(1967)20:5<891::aid-cncr2820200550>3.0.co;2-v.
7
The distribution of 3H-bleomycin in mouse tissue.3H-博来霉素在小鼠组织中的分布。
J Antibiot (Tokyo). 1968 Nov;21(11):638-42. doi: 10.7164/antibiotics.21.638.
8
Experimental studies on the chemotherapy of brain tumors. 2. Localization of cytostatic agents in central nervous tissue after intravenous, intracarotid and intrathecal administration.脑肿瘤化疗的实验研究。2. 静脉内、颈内及鞘内给药后细胞抑制剂在中枢神经组织中的定位
Med J Osaka Univ. 1968 Mar;18(4):389-95.
9
Uptake of tritiated methotrexate by mouse brain tumors after intravenous or intrathecal administration.静脉或鞘内注射后,小鼠脑肿瘤对氚标记甲氨蝶呤的摄取。
J Neurosurg. 1974 Jun;40(6):706-16. doi: 10.3171/jns.1974.40.6.0706.
10
The uptake, distribution and anti-tumor activity of bleomycin in gliomas in the mouse.
Eur J Cancer (1965). 1974 Mar;10(3):137-42. doi: 10.1016/0014-2964(74)90145-5.