大鼠肾脏肾小球中组氨酸脱羧酶介导的组胺合成。
Histidine decarboxylase-mediated histamine synthesis in glomeruli from rat kidneys.
作者信息
Heald J I, Hollis T M
出版信息
Am J Physiol. 1976 May;230(5):1349-53. doi: 10.1152/ajplegacy.1976.230.5.1349.
Abstract
Enzymatic histamine synthesis by renal glomeruli of the rat has been examined. Assays of the partially purified enzyme demonstrated a pH optimum of 6.2, a Michaelis-Menten constant of 2.4 X 10(-4) histidine, and lack of potentiation by benzene. These data thus indicate that renal glomeruli contain the histidine-specific histidine decarboxylase.
摘要
已对大鼠肾小球的组胺酶促合成进行了研究。对部分纯化的酶进行的测定表明，其最适pH值为6.2，米氏常数为2.4×10⁻⁴组氨酸，且不受苯的增强作用。因此，这些数据表明肾小球含有组氨酸特异性组氨酸脱羧酶。
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