Lynch W S, Martin J S, Roenigk H H
Cutis. 1977 Oct;20(4):477-80.
PUVA therapy has proved to be beneficial for dermatologic conditions such as psoriasis, vitiligo, and mycosis fungoides. Attempts have been made to treat other diseases with the modality; five patients with pityriasis rubra pilaris were treated, with only a partial response noted in one. A poor to fair response was seen in treating a small group of patients with cystic acne, atopic dermatitis, and neurodermatitis. As might be expected, no response was seen in one patient with Darier's disease. At present, photochemotherapy must be viewed with cautious optimism. Strict adherence to a rational treatment approach and close longterm follow-up observations are essential for determining the safety of this modality.
补骨脂素加紫外线A（PUVA）疗法已被证明对银屑病、白癜风和蕈样肉芽肿等皮肤病有效。人们已尝试用这种方法治疗其他疾病；对5例毛发红糠疹患者进行了治疗，仅1例有部分反应。在治疗一小群囊性痤疮、特应性皮炎和神经性皮炎患者时，观察到反应不佳至一般。不出所料，1例 Darier病患者无反应。目前，对光化学疗法必须持谨慎乐观的态度。严格遵循合理的治疗方法并进行长期密切随访观察对于确定这种治疗方式的安全性至关重要。
