Comparative fates of intravenously and orally administered aldosterone: evidence for extrahepatic formation of acid-hydrolyzable conjugate in man.
作者信息
Bledsoe T, Liddle G W, Riondel A, Island D P, Bloomfield D, Sinclair-Smith B
出版信息
J Clin Invest. 1966 Feb;45(2):264-9. doi: 10.1172/JCI105339.
Abstract
摘要
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Comparative fates of intravenously and orally administered aldosterone: evidence for extrahepatic formation of acid-hydrolyzable conjugate in man.静脉注射和口服醛固酮的比较转归：人体中酸可水解共轭物肝外形成的证据。
J Clin Invest. 1966 Feb;45(2):264-9. doi: 10.1172/JCI105339.
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Contribution to the study of the structure of the aldosterone-conjugate isolated from human urine.对从人尿中分离出的醛固酮结合物结构研究的贡献
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The metabolism of orally and intravenously administered labeled aldosterone in pregnant subjects.妊娠受试者口服和静脉注射标记醛固酮后的代谢情况。
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Studies on phenolic steroids in human subjects. XVI. Role of the kidney in the disposition of estriol.人体中酚类甾体的研究。第十六部分。肾脏在雌三醇代谢中的作用。
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A comparison of the metabolism of radioactive 17-isoaldosterone and aldosterone administered intravenously and orally to normal human subjects.对正常人类受试者静脉注射和口服放射性17-异醛固酮及醛固酮后的代谢情况进行比较。
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Further experimental evidence for the formation of the acid hydrolyzable conjugate of aldosterone by the kidney.肾脏形成醛固酮酸可水解共轭物的进一步实验证据。
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Determination of small amounts of 18-aldosterone glucuronide in urine.尿液中痕量18-醛固酮葡萄糖醛酸苷的测定
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A comparison of the metabolism of radioactive 17-isoaldosterone and aldosterone administered intravenously and orally to normal human subjects.对正常人类受试者静脉注射和口服放射性17-异醛固酮及醛固酮后的代谢情况进行比较。
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The metabolism of orally and intravenously administered labeled aldosterone in pregnant subjects.妊娠受试者口服和静脉注射标记醛固酮后的代谢情况。
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本文引用的文献
1
Double isotope derivative assay of aldosterone in biological extracts.生物提取物中醛固酮的双同位素衍生物测定法。
J Biol Chem. 1960 Jun;235:1639-48.
2
Aldosterone metabolism in liver disease.肝脏疾病中的醛固酮代谢
Acta Endocrinol (Copenh). 1960 Feb;33:168-74. doi: 10.1530/acta.0.xxxiii0168.
3
[RENAL CLEARANCE OF ALDOSTERONE AND ITS METABOLITE IN MAN].[人体中醛固酮及其代谢产物的肾脏清除率]
Acta Endocrinol (Copenh). 1965 Aug;49:510-24.
4
CONJUGATION OF 1,2-3H-ALDOSTERONE IN HUMAN LIVER AND KIDNEYS AND RENAL EXTRACTION OF ALDOSTERONE AND LABELED CONJUGATES FROM BLOOD PLASMA.人肝脏和肾脏中1,2-³H-醛固酮的结合以及醛固酮和标记结合物从血浆中的肾脏提取
J Clin Endocrinol Metab. 1965 May;25:628-38. doi: 10.1210/jcem-25-5-628.
5
SPLANCHNIC EXTRACTION AND CLEARANCE OF ALDOSTERONE IN SUBJECTS WITH MINIMAL AND MARKED CARDIAC DYSFUNCTION.轻度和重度心功能不全患者醛固酮的内脏提取与清除
J Clin Endocrinol Metab. 1965 Feb;25:219-28. doi: 10.1210/jcem-25-2-219.
6
PURIFICATION, PARTIAL CHARACTERIZATION AND METABOLISM OF AN ACID LABILE CONJUGATE OF ALDOSTERONE.醛固酮酸不稳定结合物的纯化、部分特性鉴定及代谢
J Clin Endocrinol Metab. 1964 Nov;24:1110-24. doi: 10.1210/jcem-24-11-1110.
7
MODIFICATION OF ALDOSTERONE SECRETION AND ELECTROLYTE EXCRETION IN MAN BY A CHEMICAL INHIBITOR OF 18-OXIDATION.
J Clin Endocrinol Metab. 1964 Aug;24:740-6. doi: 10.1210/jcem-24-8-740.
8
ALDOSTERONE SECRETION AND METABOLISM IN HYPERTHYROIDISM AND MYXEDEMA.
J Clin Endocrinol Metab. 1963 Sep;23:873-80. doi: 10.1210/jcem-23-9-873.
9
The metabolism of aldosterone. II.
Acta Endocrinol (Copenh). 1962 Jan;39:87-102. doi: 10.1530/acta.0.0390087.
10
The metabolism of aldosterone in normal subjects and in patients with hepatic cirrhosis.正常受试者及肝硬化患者体内醛固酮的代谢
J Clin Invest. 1962 Aug;41(8):1672-80. doi: 10.1172/JCI104624.
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