Thatcher F S
Can Med Assoc J. 1966 Mar 19;94(12):582-90.
Food poisoning caused by the ingestion of preformed bacterial toxins is considered in relation to comparative symptoms, procedures for extraction and purification of the causal toxins, their chemistry, serology, assay procedures and pharmacology, in so far as these are known.The bacteria discussed in this context are Clostridium botulinum, C. perfringens, Staphylococcus aureus, Bacillus cereus, and Vibrio parahemolyticus. The possible roles of the enterococci, Proteus, E. coli and of unknown species, in relation to production of non-antigenic toxic substances, are discussed briefly.Requirements for prevention of the various forms of bacterial food poisoning are outlined.
本文探讨了因摄入预先形成的细菌毒素而导致的食物中毒,涉及已知的比较症状、致病毒素的提取和纯化程序、其化学性质、血清学、检测程序及药理学。本文讨论的细菌有肉毒梭菌、产气荚膜梭菌、金黄色葡萄球菌、蜡样芽孢杆菌和副溶血性弧菌。还简要讨论了肠球菌、变形杆菌、大肠杆菌及未知菌种在产生非抗原性有毒物质方面可能发挥的作用。概述了预防各种细菌性食物中毒的要求。