乳糜泻患者十二指肠黏膜中5-羟色胺的组织浓度升高。
Increased tissue concentrations of 5-hydroxytryptamine in the duodenal mucosa of patients with coeliac disease.
作者信息
Challacombe D N, Dawkins P D, Baker P
出版信息
Gut. 1977 Nov;18(11):882-6. doi: 10.1136/gut.18.11.882.
Abstract
Tissue concentrations of 5-HT have been measured in the duodenal mucosa of adults and children with coeliac disease and were found to be significantly higher than those from a control group. This finding may be associated with hyperactivity or hyperplasia of enterochromaffin (EC) cells in the duodenum of patients with coeliac disease and could also be directly related to described abnormalities of 5-HT metabolism in this disease.
摘要
已对患有乳糜泻的成人和儿童十二指肠黏膜中的5-羟色胺（5-HT）组织浓度进行了测量，发现其显著高于对照组。这一发现可能与乳糜泻患者十二指肠中肠嗜铬（EC）细胞的活性过高或增生有关，也可能与该疾病中所描述的5-HT代谢异常直接相关。
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