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脱氨基催产素和1-γ-巯基丁酸催产素:X射线晶体学数据。

Deamino-oxytocin and 1-gamma-mercaptobutyric acid-oxytocin: x-ray crystallographic data.

作者信息

Low B W, Chen C C

出版信息

Science. 1966 Mar 25;151(3717):1552-3. doi: 10.1126/science.151.3717.1552.

DOI:10.1126/science.151.3717.1552
PMID:5909592
Abstract

X-ray studies of crystalline deamino-oxytocin (1-beta-mercaptopropionic acid-oxytocin) have established the existence of both wet and dry forms. A remarkable degree of similarity exists between the two forms even though there are changes in cell dimensions and space group on drying. The dry form of 1-gamma-mercaptobutyric acid-oxytocin is very similar to that of deamino-oxytocin.

摘要

对结晶去氨基催产素(1-β-巯基丙酸-催产素)的X射线研究已证实存在湿态和干态两种形式。尽管干燥后晶胞尺寸和空间群发生了变化,但两种形式之间仍存在显著程度的相似性。1-γ-巯基丁酸-催产素的干态与去氨基催产素的干态非常相似。

相似文献

1
Deamino-oxytocin and 1-gamma-mercaptobutyric acid-oxytocin: x-ray crystallographic data.脱氨基催产素和1-γ-巯基丁酸催产素:X射线晶体学数据。
Science. 1966 Mar 25;151(3717):1552-3. doi: 10.1126/science.151.3717.1552.
2
The effect of increasing the size of the ring present in deamino-oxytocin by one methylene group on its biological properties. The synthesis of 1-gamma-mercaptobutyric acid-oxytocin.在脱氨基催产素中使环的大小增加一个亚甲基对其生物学性质的影响。1-γ-巯基丁酸-催产素的合成。
J Biol Chem. 1965 Sep;240(9):3553-7.
3
The conformation of deamino-oxytocin: X-ray analysis of the 'dry' and 'wet' forms.
Philos Trans R Soc Lond B Biol Sci. 1990 Apr 27;327(1243):625-54. doi: 10.1098/rstb.1990.0103.
4
The effect of replacing one of the hydrogens of the beta-carbon of the beta-mercaptopropionic acid residue in deamino-oxytocin by a methyl group on its oxytocic and avian vasodepressor activity.在脱氨基催产素中,将β-巯基丙酸残基β-碳上的一个氢原子用甲基取代对其催产活性和禽类血管减压活性的影响。
J Am Chem Soc. 1966 Nov 5;88(21):5015-8. doi: 10.1021/ja00973a043.
5
Oxytocin: crystal data of a seleno analog.催产素:一种硒代类似物的晶体数据。
Science. 1969 Feb 28;163(3870):925-6. doi: 10.1126/science.163.3870.925.
6
The synthesis and pharmacological properties of deamino-4-decarboxamido-oxytocin (1-beta-mercaptopropionic acid-1-alpha-aminobutyric acid-oxytocin).去氨基-4-脱羧酰胺基催产素(1-β-巯基丙酸-1-α-氨基丁酸-催产素)的合成及药理特性
J Biol Chem. 1966 Jun 10;241(11):2572-5.
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7-D-proline-oxytocin and its deamino analog. Diastereoisomers of oxytocin and deamino-oxytocin.7-D-脯氨酸-催产素及其脱氨基类似物。催产素和脱氨基催产素的非对映异构体。
J Am Chem Soc. 1966 Aug 20;88(16):3847-50. doi: 10.1021/ja00968a032.
8
CRYSTALLINE DEAMINO-OXYTOCIN.
Science. 1964 Feb 7;143(3606):545-8. doi: 10.1126/science.143.3606.545.
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Secondary structure of the cyclic moiety of the peptide hormone oxytocin and its deamino analog.肽激素催产素及其脱氨基类似物环状部分的二级结构。
Proc Natl Acad Sci U S A. 1970 May;66(1):111-6. doi: 10.1073/pnas.66.1.111.
10
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding.
Science. 1986 May 2;232(4750):633-6. doi: 10.1126/science.3008332.