Mandell A J, Chaffey B, Brill P, Mandell M P, Rodnick J, Rubin R T, Sheff R
Science. 1966 Mar 25;151(3717):1558-60. doi: 10.1126/science.151.3717.1558.
Epochs of dreaming sleep, as measured by rapid eye movements, consistently correlated with biphasic change in urine volume and osmolality in catheterized human subjects. Marked decrease in volumne and increase in oslnolality were followed by a hypotonic diuresis.