Fox H
J Clin Pathol. 1966 Mar;19(2):133-7. doi: 10.1136/jcp.19.2.133.
A series of six placental haemangiomata is described. Of these one was large and was associated clinically with hydramnios and premature labour. The remaining five were discovered in the course of a systemic examination of 500 unselected placentae. The literature on this tumour is reviewed and it is concluded that this is a very common lesion occurring in about 1% of all placentae. The tumour is probably hamartomatous in nature and is derived from primitive chorionic mesenchyme. Most tumours are small and intraplacental and are not associated with any clinical side effects. The comparatively small group of large haemangiomata do show an association with hydramnios, premature labour, low birth weight, foetal distress and, in a few instances, cardiomegaly in the infant.
本文描述了一系列六个胎盘血管瘤。其中一个较大，临床上与羊水过多和早产相关。其余五个是在对500个未经挑选的胎盘进行系统检查过程中发现的。本文回顾了关于这种肿瘤的文献，并得出结论，这是一种非常常见的病变，约占所有胎盘的1%。该肿瘤本质上可能是错构瘤，起源于原始绒毛膜间充质。大多数肿瘤较小且位于胎盘内，不伴有任何临床副作用。相对少数的大血管瘤确实与羊水过多、早产、低出生体重、胎儿窘迫有关，在少数情况下，还与婴儿心脏肥大有关。
