大鼠中的类过敏反应。
Anaphylactoid responses in rats.
作者信息
West G B
出版信息
Int Arch Allergy Appl Immunol. 1977;55(1-6):542-5. doi: 10.1159/000231969.
The relative activities of dextran, mannan and ovomucoid as agents inducing anaphylactoid responses in rats vary with the route of injection, mannan being the most active especially by the intradermal route. All of these responses are potentiated by pretreatment with insulin and inhibited by glucose. Carrageenan and concanavalin A are also active but only by the subcutaneous route. Whereas the concanavalin A response is potentiated by insulin, that of carrageenan is reduced. There are therefore at least three classes of agents capable of inducing anaphylactoid responses in rats.
右旋糖酐、甘露聚糖和卵类粘蛋白作为诱导大鼠类过敏反应的介质，其相对活性随注射途径而异，甘露聚糖最为活跃，尤其是通过皮内途径。所有这些反应都因胰岛素预处理而增强，因葡萄糖而受到抑制。角叉菜胶和伴刀豆球蛋白A也有活性，但仅通过皮下途径。伴刀豆球蛋白A的反应因胰岛素而增强，而角叉菜胶的反应则减弱。因此，至少有三类介质能够在大鼠中诱导类过敏反应。
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