Local anaphylactoid responses in rats.

The relative activities of 15 agents inducing anaphylactoid responses in the paws of two types of genetically different rats have been determined. Three groups were identified: group 1, where activity was much higher in R rats than in NR rats; group 2 where activity was low in both R and NR rats, and group 3, where activity was equally high in both R and NR rats. The influence of changes in the blood sugar level on these responses was also investigated in the three groups.