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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Biochem J. 1966 Mar;98(3):898-902. doi: 10.1042/bj0980898.

The respiration and aerobic glycolysis of pig ciliary processes in oxygenated phosphate and bicarbonate buffers have been investigated. 2. Significant amounts of lactic acid are produced only in the presence of added glucose, but this does not change the endogenous respiration rate. 3. Succinate and citrate increase the oxygen uptake considerably, but pyruvate has almost no effect; oxaloacetate and fumarate stimulate slightly in the presence of glucose. Aspartate and fumarate together stimulate pyruvate utilization and are oxidized as fast as citrate. 4. Ouabain inhibits the oxidation of glucose and other substrates by limiting the ADP supply from the sodium transport system. Cyanide and azide inhibit respiration and stimulate glycolysis. 5. The transport mechanism depends largely on ATP from oxidative phosphorylation and regulates the rate of respiration and glycolysis by controlling ADP production from the Na(+)-K(+)-activated adenosine triphosphatase.

已对猪睫状体在含氧磷酸盐和碳酸氢盐缓冲液中的呼吸作用及有氧糖酵解进行了研究。2. 仅在添加葡萄糖的情况下才会产生大量乳酸，但这并不改变内源性呼吸速率。3. 琥珀酸和柠檬酸可显著增加氧气摄取量，但丙酮酸几乎没有影响；在有葡萄糖存在的情况下，草酰乙酸和富马酸有轻微刺激作用。天冬氨酸和富马酸共同刺激丙酮酸的利用，且氧化速度与柠檬酸一样快。4. 哇巴因通过限制钠转运系统提供的二磷酸腺苷（ADP）来抑制葡萄糖和其他底物的氧化。氰化物和叠氮化物抑制呼吸作用并刺激糖酵解。5. 转运机制在很大程度上依赖于氧化磷酸化产生的三磷酸腺苷（ATP），并通过控制钠钾激活的三磷酸腺苷酶产生的ADP来调节呼吸作用和糖酵解的速率。

Biochem J. 1966 Mar;98(3):898-902. doi: 10.1042/bj0980898.

The respiration and aerobic glycolysis of pig ciliary processes in oxygenated phosphate and bicarbonate buffers have been investigated. 2. Significant amounts of lactic acid are produced only in the presence of added glucose, but this does not change the endogenous respiration rate. 3. Succinate and citrate increase the oxygen uptake considerably, but pyruvate has almost no effect; oxaloacetate and fumarate stimulate slightly in the presence of glucose. Aspartate and fumarate together stimulate pyruvate utilization and are oxidized as fast as citrate. 4. Ouabain inhibits the oxidation of glucose and other substrates by limiting the ADP supply from the sodium transport system. Cyanide and azide inhibit respiration and stimulate glycolysis. 5. The transport mechanism depends largely on ATP from oxidative phosphorylation and regulates the rate of respiration and glycolysis by controlling ADP production from the Na(+)-K(+)-activated adenosine triphosphatase.

已对猪睫状体在含氧磷酸盐和碳酸氢盐缓冲液中的呼吸作用及有氧糖酵解进行了研究。2. 仅在添加葡萄糖的情况下才会产生大量乳酸，但这并不改变内源性呼吸速率。3. 琥珀酸和柠檬酸可显著增加氧气摄取量，但丙酮酸几乎没有影响；在有葡萄糖存在的情况下，草酰乙酸和富马酸有轻微刺激作用。天冬氨酸和富马酸共同刺激丙酮酸的利用，且氧化速度与柠檬酸一样快。4. 哇巴因通过限制钠转运系统提供的二磷酸腺苷（ADP）来抑制葡萄糖和其他底物的氧化。氰化物和叠氮化物抑制呼吸作用并刺激糖酵解。5. 转运机制在很大程度上依赖于氧化磷酸化产生的三磷酸腺苷（ATP），并通过控制钠钾激活的三磷酸腺苷酶产生的ADP来调节呼吸作用和糖酵解的速率。