Marshall W H, Melman S
Clin Exp Immunol. 1966 Apr;1(2):189-93.
Antibody production against the mitogenic principle of extract Phytohaemagglutinin' has been measured in a sheep and in three patients with aplastic anaemia treated with Phytohaemagglutinin'. (A fourth patient produced no measurable antibody.) The antibody production curve has some of the characteristics of a primary response and was compared with results of a second immunization in the case of the sheep. The titrations depended on the leucocyte culture method as a biological indicator of mitogenic activity.
已在一只绵羊以及三名接受“植物血凝素”治疗的再生障碍性贫血患者体内,检测了针对“植物血凝素”提取物促有丝分裂原理的抗体产生情况。(第四名患者未产生可检测到的抗体。)抗体产生曲线具有一些初次反应的特征,并与绵羊再次免疫的结果进行了比较。滴定取决于白细胞培养方法,将其作为促有丝分裂活性的生物学指标。