Ebner H, Jurecka W
J Cutan Pathol. 1977 Sep;4(4):185-90. doi: 10.1111/j.1600-0560.1977.tb00906.x.
In seven patients suffering from lichen planus (LP) light- and electron-microscopic 3H-thymidine (3HT) labeling studies were performed and the following results were obtained. 1. Using the light-microscope, a large number of 3HT labeled cells can be observed in the dermal infiltrate of LP. Most of the labeled nuclei belong to mononuclear, 'round cells' while isolated endothelial cells, fibroblasts, histiocytes and mast cells could be found labeled. 2. The mean labeling index of 'round cells' in our patients was 4.27 +/- 1.57%. 3. The evaluation of the electron microscopic autoradiographs showed that, as far as 'round' cells were concerned, exclusively nuclei of cells showing the morphological criteria of stimulated lymphocytes were labeled. These findings support the view that in LP, as in allergic contact dermatitis, a high proliferative activity of lymphocytes takes place.
对7例扁平苔藓（LP）患者进行了光镜和电镜下的3H-胸腺嘧啶核苷（3HT）标记研究，结果如下。1. 用光镜观察，在LP的真皮浸润中可观察到大量3HT标记细胞。大多数标记核属于单核“圆形细胞”，同时可发现孤立的内皮细胞、成纤维细胞、组织细胞和肥大细胞被标记。2. 我们患者中“圆形细胞”的平均标记指数为4.27±1.57%。3. 对电镜放射自显影片的评估显示，就“圆形”细胞而言，仅显示受刺激淋巴细胞形态学标准的细胞的核被标记。这些发现支持了这样一种观点，即LP与过敏性接触性皮炎一样，淋巴细胞具有高增殖活性。
