McBride R A, Schierman L W
Science. 1966 Nov 4;154(3749):655-7. doi: 10.1126/science.154.3749.655.
Spleen cells were obtained from chickens stimulated simultaneously with different erythrocytic antigens, and the proportions producing one and two antibodies were determined by the hemolytic-plaque technique. Most cells from birds immunized with two antigens of the same system (B) appeared to produce only one antibody. In a population of cells from birds immunized with antigens of different systems (A and B), a relatively high proportion of cells produced two antibodies.
从同时用不同红细胞抗原刺激的鸡身上获取脾细胞，并通过溶血空斑技术确定产生一种和两种抗体的细胞比例。用同一系统（B）的两种抗原免疫的鸡的大多数细胞似乎只产生一种抗体。在用不同系统（A和B）的抗原免疫的鸡的细胞群体中，产生两种抗体的细胞比例相对较高。
