Studies of in vitro primaquine hemolysis: substrate requirement for erythrocyte membrane damage.
作者信息
George J N, O'Brien R L, Pollack S, Crosby W H
出版信息
J Clin Invest. 1966 Aug;45(8):1280-9. doi: 10.1172/JCI105435.
Abstract
摘要
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Studies of in vitro primaquine hemolysis: substrate requirement for erythrocyte membrane damage.体外伯氨喹溶血研究：红细胞膜损伤的底物需求
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Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes.形成伯氨喹-5,6-邻醌，伯氨喹在人红细胞内通过直接氧化产生的潜在活性和毒性代谢物。
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Drug-induced erythrocyte membrane internalization.药物诱导的红细胞膜内化。
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本文引用的文献
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THE OSMOTIC RESISTANCE (FRAGILITY) OF HUMAN RED CELLS.人类红细胞的渗透抵抗力（脆性）
J Clin Invest. 1947 Jul;26(4):636-40. doi: 10.1172/JCI101847.
2
Toxicity of primaquine in Negroes.伯氨喹对黑人的毒性。
J Am Med Assoc. 1952 Aug 23;149(17):1568-70. doi: 10.1001/jama.1952.72930340027010c.
3
Toxicity of primaquine in Caucasians.伯氨喹对高加索人的毒性。
J Am Med Assoc. 1952 Aug 23;149(17):1563-8. doi: 10.1001/jama.1952.72930340022010b.
4
The pathogenesis of spherocytes and leptocytes (target cells).
Blood. 1952 Feb;7(2):261-74.
5
A metabolite of pamaquine from chickens.来自鸡的伯氨喹代谢物。
J Pharmacol Exp Ther. 1951 Sep;103(1):7-9.
6
A metabolic intermediate of pamaquine from chickens.
Proc Soc Exp Biol Med. 1951 Apr;76(4):700-3. doi: 10.3181/00379727-76-18599.
7
Effects of sulfhydryl inhibition on red blood cells. I. Mechanism of hemolysis.巯基抑制对红细胞的影响。I. 溶血机制。
J Clin Invest. 1962 Apr;41(4):779-92. doi: 10.1172/JCI104536.
8
OXIDATIVE HEMOLYSIS AND ERYTHROCYTE METABOLISM IN HEREDITARY ACATALASIA.遗传性无过氧化氢酶血症中的氧化溶血与红细胞代谢
J Clin Invest. 1965 Jul;44(7):1187-99. doi: 10.1172/JCI105225.
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LOCALIZATION OF ERYTHROCYTE MEMBRANE SULFHYDRYL GROUPS ESSENTIAL FOR GLUCOSE TRANSPORT.葡萄糖转运所需红细胞膜巯基的定位
J Gen Physiol. 1965 Mar;48(4):617-32. doi: 10.1085/jgp.48.4.617.
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