Ogston C M, Ogston D
J Clin Pathol. 1966 Jul;19(4):352-6. doi: 10.1136/jcp.19.4.352.
Plasma fibrinogen and plasminogen levels were measured in 122 male and 56 female healthy adult subjects and in 64 men with ischaemic heart disease. Plasma fibrinogen levels were found to rise markedly and progressively with age in both male and female healthy subjects; plasminogen showed only a slight rise with age. No sex differences were found for either fibrinogen or plasminogen. The correlation between plasminogen and fibrinogen levels was low, reaching the 5% level of significance only in men. Patients with ischaemic heart disease were found to have significantly increased fibrinogen and plasminogen levels in the 31-45 years age group only.
对122名男性和56名女性健康成年受试者以及64名患有缺血性心脏病的男性进行了血浆纤维蛋白原和纤溶酶原水平的测定。在男性和女性健康受试者中,血浆纤维蛋白原水平均随年龄显著且逐渐升高;纤溶酶原仅随年龄略有升高。纤维蛋白原和纤溶酶原均未发现性别差异。纤溶酶原与纤维蛋白原水平之间的相关性较低,仅在男性中达到5%的显著性水平。仅在31 - 45岁年龄组的缺血性心脏病患者中发现纤维蛋白原和纤溶酶原水平显著升高。