McQueen E G, Engel G B
J Clin Pathol. 1966 Jul;19(4):392-6. doi: 10.1136/jcp.19.4.392.
The factors determining aggregation of Tamm-Horsfall urinary mucoprotein have been examined using the technique of light-scattering photometry, which has allowed the study to be performed at the concentrations of the mucoprotein in which it occurs in the urine in vivo. The tendency to formation of aggregates is enhanced by increases in concentration of the mucoprotein, by increases in electrolyte concentration within physiological limits, and by lowering of the pH within the physiological range. The effects of 1:2 and 2:1 electrolytes are somewhat different from those of 1:1 electrolytes. The data suggest that the isoelectric point of Tamm-Horsfall protein is higher than previously thought.
利用光散射光度法技术研究了决定Tamm-Horsfall尿粘蛋白聚集的因素，该技术使研究能够在粘蛋白于体内尿液中存在的浓度下进行。粘蛋白浓度的增加、生理范围内电解质浓度的增加以及生理范围内pH值的降低都会增强聚集物形成的倾向。1:2和2:1电解质的作用与1:1电解质的作用略有不同。数据表明，Tamm-Horsfall蛋白的等电点高于先前的认识。
