衰老的演化

Nature. 1977 Nov 24;270(5635):301-4. doi: 10.1038/270301a0.

An evolutionary view of ageing suggests that mortality may be due to an energy-saving strategy of reduced error regulation in somatic cells. This supports Orgel's 'error catastrophe' hypothesis and offers a new basis for the study of normal and abnormal ageing syndromes and of apparently immortal transformed cell lines.

衰老的进化观点表明，死亡率可能是由于体细胞中错误调节减少的一种节能策略所致。这支持了奥格尔的“错误灾难”假说，并为研究正常和异常衰老综合征以及明显永生的转化细胞系提供了新的基础。