Fischetti M R, Carey W, Baher C C
Oncology. 1977;34(6):264-6. doi: 10.1159/000225239.
A review of the last seventy-eight consecutive cases of Hodgkin's disease seen at our hospital revealed that two presented several hematologic cytopenias. These two cases and a similar case first seen at an associated hospital revealed pancytopenia in two and leukopenia in the third. All responded to splenectomy with hematologic improvement. All met the criteria for hypersplenism. This report illustrates that Hodgkin's disease can present cytopenias due to hypersplenism, and that early splenectomy can lead to hematologic improvement and tolerance of subsequent chemotherapy.
对我院连续收治的78例霍奇金病患者的回顾显示，其中2例出现了多种血细胞减少症。这2例患者以及1例首先在相关医院就诊的类似病例，其中2例出现全血细胞减少，第3例出现白细胞减少。所有患者脾切除术后血液学指标均有改善。所有患者均符合脾功能亢进的标准。本报告表明，霍奇金病可因脾功能亢进导致血细胞减少，早期脾切除可使血液学指标改善，并提高对后续化疗的耐受性。
