Fialk M A, Coleman M, Grant M D, Pasmantier M W, Silver R T
Am J Med Sci. 1977 Jul-Aug;274(1):87-91. doi: 10.1097/00000441-197707000-00013.
Two patients with Hodgkin's disease and hypoplastic bone marrow underwent splenectomy in an attempt to reverse pancytopenia and to improve chemotherapeutic tolerance. Although the peripheral blood counts were improved, the clinical course was not significantly affected. Infectious complications occurred. This suggests that the peripheral hematologic improvement following splenectomy may not reflect a true improvement in marrow tolerance.
两名患有霍奇金病和骨髓发育不全的患者接受了脾切除术，试图逆转全血细胞减少并提高化疗耐受性。尽管外周血细胞计数有所改善，但临床病程并未受到显著影响。出现了感染性并发症。这表明脾切除术后外周血液学的改善可能并不反映骨髓耐受性的真正改善。
