Toth B, Shubik P
Science. 1966 Jun 3;152(3727):1376-7. doi: 10.1126/science.152.3727.1376.
The occurrence of manomary adenocarcinonmas in C3H mice is largely inhibited by prolonged admninistration of 0.1 percent isonicotinic acid hydrazide in drinking water. At the same time that this compound produtced the inhibitory action, it also increased the incidence of pulmonary adenomas.
在C3H小鼠中,通过在饮用水中长时间给予0.1%的异烟肼,可在很大程度上抑制乳腺腺癌的发生。在该化合物产生抑制作用的同时,它还增加了肺腺瘤的发生率。