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源自流感病毒的包膜蛋白。

Envelope protein(s) derived from influenza virus.

作者信息

Eckert E A

出版信息

J Bacteriol. 1966 May;91(5):1907-10. doi: 10.1128/jb.91.5.1907-1910.1966.

DOI:10.1128/jb.91.5.1907-1910.1966
PMID:5937246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC316143/
Abstract

Eckert, Edward A. (University of Michigan, Ann Arbor). Envelope protein(s) derived from influenza virus. J. Bacteriol. 91:1907-1910. 1966.-Lipids were extracted from influenza virus, strain PR8, with methanol-chloroform, and the protein residue was dissolved in 67% glacial acetic acid. Hemagglutinating activity and complement-fixing reactivity were markedly reduced or lost during lipid extraction, and then increased after acetic acid treatment and subsequent dialysis. Evidence is presented that the envelope protein(s) responsible for these activities is dissociated in acetic acid and reassociated at neutral pH.

摘要

埃克特,爱德华·A.(密歇根大学,安阿伯分校)。源自流感病毒的包膜蛋白。《细菌学杂志》91:1907 - 1910。1966年。——用甲醇 - 氯仿从PR8株流感病毒中提取脂质,蛋白质残渣溶解于67%的冰醋酸中。在脂质提取过程中,血凝活性和补体结合反应性显著降低或丧失,而在醋酸处理及随后的透析后又有所增加。有证据表明,负责这些活性的包膜蛋白在醋酸中解离,并在中性pH下重新结合。

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J Hyg (Lond). 1969 Jun;67(2):301-10. doi: 10.1017/s002217240004170x.
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2
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Virology. 1964 Nov;24:426-33. doi: 10.1016/0042-6822(64)90180-1.
3
STRUCTURAL STUDIES ON THE PROTEIN SUBUNITS FROM THREE STRAINS OF INFLUENZA VIRUS.三种流感病毒株蛋白质亚基的结构研究
J Mol Biol. 1964 Jul;9:109-24. doi: 10.1016/s0022-2836(64)80094-2.
4
THE DISSOCIATION AND ASSOCIATION OF PROTEIN STRUCTURES.蛋白质结构的解离与缔合
Adv Protein Chem. 1963;18:123-226. doi: 10.1016/s0065-3233(08)60269-7.
5
PHYSICAL AND IMMUNOLOGICAL PROPERTIES OF A SOLUBLE PRECURSOR OF THE POLIOVIRUS CAPSID.脊髓灰质炎病毒衣壳可溶性前体的物理和免疫学特性
Proc Natl Acad Sci U S A. 1964 Feb;51(2):329-37. doi: 10.1073/pnas.51.2.329.
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