Yatvin M B
Science. 1966 Jul 8;153(3732):184-5. doi: 10.1126/science.153.3732.184.
The normal sequence of molecular events which occurs during feather and skin differentiation in the chick embryo is interrupted by pituitary gland ablation. The characteristic pattern of development is reestablished in hypophysectomized embryos treated with pituitary extract and in hypophysectomized embryos in parabiotic union with their twins within a double-yolked egg. These results suggest that genetic expression in differentiating chick feather and skin after day 12 of incubation is regulated by hormones.
在鸡胚羽毛和皮肤分化过程中发生的正常分子事件序列会被垂体切除所中断。在用垂体提取物处理的垂体切除胚胎以及与双黄蛋内的双胞胎联体的垂体切除胚胎中，特征性的发育模式得以重新建立。这些结果表明，孵化12天后分化的鸡羽毛和皮肤中的基因表达受激素调控。
