Cumming W J, Weiser R, Teoh R, Hudgson P, Walton J N
Q J Med. 1977 Oct;46(184):531-46.
Three cases of a painful, inflammatory, nodular myopathy in young and middle-aged adult males are described. In two of the cases the nodular process gradually evolved into a diffuse proximal myopathy accompanied by dysphagia, and manifesting the so-called "facioscapulohumeral syndrome". The electromyogram (EMG) in all three cases was "myopathic" in type and in two cases abnormalities consistent with an inflammatory muscle disorder were seen. Muscle biopsy revealed a consistent pattern of intense, predominantly interstitial, pleomorphic infiltration of muscle with scattered foci of muscle fibre destruction and regeneration, which resembled muscle infarcts. It is suggested that this syndrome, whilst readily recognizable from both the clinical and pathological standpoints, is not a nosological entity in its own right but rather an unusual presentation of polymyositis.
本文描述了3例发生于中青年男性的疼痛性、炎症性结节性肌病。其中2例患者的结节性病变逐渐演变为弥漫性近端肌病，并伴有吞咽困难，表现出所谓的“面肩肱型综合征”。所有3例患者的肌电图（EMG）均呈“肌病性”类型，2例可见与炎症性肌肉疾病相符的异常表现。肌肉活检显示出一致的模式，即肌肉有强烈的、主要为间质的多形性浸润，伴有散在的肌纤维破坏和再生灶，类似肌肉梗死。有人认为，该综合征虽然从临床和病理学角度都易于识别，但它本身并非一个独立的病种，而是多肌炎的一种不寻常表现形式。
