Paez P N, Burchak E C, Herbert F A
Can Med Assoc J. 1966 Jun 18;94(25):1311-3.
Mycobacterium tuberculosis and the atypical mycobacteria may give rise to similar clinical pictures. Although the etiological separation of these diseases requires special cultural techniques, the identity of the causative mycobacteria may be suggested following the simultaneous use of a series of antigens. Thus, in spite of cross-reactivity to photochromogen and to a lesser degree to scotochromogen antigens, patients with typical tuberculosis had the largest reaction to Old Tuberculin. Such simultaneous tests, when carried out with careful measurements in a standardized manner, are of diagnostic value in identifying the responsible mycobacterium.
结核分枝杆菌和非典型分枝杆菌可能引发相似的临床症状。尽管这些疾病的病因学区分需要特殊的培养技术，但同时使用一系列抗原后，可能提示致病分枝杆菌的种类。因此，尽管对光产色菌抗原存在交叉反应，对暗产色菌抗原的交叉反应程度较轻，但典型结核病患者对旧结核菌素的反应最大。当以标准化方式进行仔细测量时，这种同步检测对于识别致病分枝杆菌具有诊断价值。
