Bornatsch W, Untch K G
Prostaglandins. 1977 Oct;14(4):617-23. doi: 10.1016/0090-6980(77)90188-5.
Both pairs of dl-11-desoxy- and dl-13-cis-erythro-15,16-dihydroxyprostaglandins have been synthesized via 1,4-conjugate additions of an appropriately functionalized cis-vinyl cuprate to the requisite cyclopentenone. These prostaglandin analogs are considerably less potent than PGE2 as gastric secretion inhibitors or as bronchodilators.
通过将适当官能化的顺式乙烯基铜酸盐与所需的环戊烯酮进行1,4-共轭加成，合成了两对dl-11-脱氧-和dl-13-顺式-赤式-15,16-二羟基前列腺素。这些前列腺素类似物作为胃分泌抑制剂或支气管扩张剂的效力比PGE2低得多。
