Kritikou P E, Branthwaite M A
Thorax. 1977 Oct;32(5):534-8. doi: 10.1136/thx.32.5.534.
A study of 100 patients requiring open-heart surgery has been undertaken to ascertain whether prophylactic measures designed to minimise cerebral damage have influenced the incidence or severity of changes in cerebral electrical activity recorded at the onset of cardiopulmonary bypass. The incidence of change in cerebral electrical activity remains high but the severity of the disturbances has diminished as compared with a series investigated before prophylactic measures were introduced. Changes suggestive of cerebral depression were particularly notable in children under 10 years of age. The significance of these findings is discussed in the context of factors which might influence cerebral electrical activity at the onset of bypass.
对100例需要进行心脏直视手术的患者进行了一项研究，以确定旨在将脑损伤降至最低的预防措施是否影响了在心肺转流开始时记录的脑电活动变化的发生率或严重程度。脑电活动变化的发生率仍然很高，但与在引入预防措施之前调查的一系列病例相比，干扰的严重程度有所降低。提示脑抑制的变化在10岁以下儿童中尤为明显。在可能影响转流开始时脑电活动的因素背景下讨论了这些发现的意义。
